PHYS 323 - Experimental Biophysics

Description:
Introduction to techniques in experimental biophysics. Topics include fluorescence microscopy, image processing, computational modeling, and statistical mechanics.

Prerequisites:
Prerequisite: PHYS 322.

Credits: (4)

Learner Outcomes, Activities and Assessments

Learner Outcome	Activity (optional)	Assessment
Design biophysics experiments, following the steps of the traditional scientific method.	They will be required to state a testable hypothesis and design experiments to systematically test their hypothesis. An example lab activities includes: (1) analyzing the motion of small particles in fluids and (2) using statistical mechanics and computer modeling to relate the particle motion to material properties of the liquid.	Graded lab reports written by individual students
Develop an original research proposal for a project to be carried out with available biophysics equipment.	Students will work in groups in class to develop research proposals for biophysics research projects. Students will be given the option to choose from a list of suggested topics or propose their own. Special attention will be given towards developing a realistic research plan, including material and equipment needs, experimental procedures, and data analysis techniques.	Graded research proposals written by individual students and in-class presentations.
Apply research methodology such as fluorescence microscopy to characterize and analyze biophysical systems.	Students will work in groups to conduct in-class laboratory investigations.	Graded lab reports written by individual students. Checklist assessment to evaluate whether proper equipment protocol is followed during lab sessions.
Summarize and critique current biophysics research articles, to demonstrate knowledge of modern experimental biophysics techniques and their applications to research.	Students will be exposed to a broad range of techniques in experimental biophysics by reading current journal articles in biophysics. Topics will highlight interdisciplinary connections between biology and physics, and will nicely supplement their lab experience by exposing them to topics and techniques that we are unable to explore in lab due to time and/or equipment constraints.	Graded literature review assignments. Peer review of student article critiques.