CHEM 432 - Biochemistry II

• Correctly use biochemical vocabulary.
• Describe the free energy changes that occur in intermediary metabolism.
• Describe reaction pathways of intermediary metabolism by naming and writing structural formulae of intermediates, naming enzymes, and naming cofactors in glycolysis, the tricarboxylic acid cycle, and beta-oxidation of fatty acids.
• Summarize intermediary metabolic pathways by naming select intermediates, enzymes, and cofactors in cholesterol synthesis, glycogen metabolism, amino acid metabolism, and nucleotide metabolism.
• Describe the cellular structural requirements and chemical steps that form an electrochemical gradient in mitochondria and how the gradient contributes to ATP synthesis (electron transport and oxidative phosphorylation).
• Describe the role of allostery, covalent modification, and hormones in the regulation of select metabolic pathways.
• Describe the chemical components and processes involved in signal transduction.